The Develop Presets in Lightroom can be a great help when processing an image to quickly achieve the particular 'look' you have in mind. Often, one click followed by a couple of refinements and it's done. Then you can move on.
It's very easy to create your own Presets (although you'll also want to collect others such as the 'Dualing GF's' described in the Blog recently by Bob DiNatale) and of course there are many others available online. Your collection can quickly grow and I'm willing to admit that some I've accumulated might never be used, but it seems a harmless addiction, particularly when individual Preset files are so tiny, and will never seriously clog up the hard drive.

But there's always a fly in the ointment, and in this case it's the evolving mess in the Presets folder. Ideally you need to be able to quickly locate the 2 or 3 Presets that might provide the adjustment you're looking to make. Obviously the value of a Preset is lost if you have to spend ages searching for it. I began to find that I could locate a specific image more quickly than a particular preset.

The solution I adopted was to create folders within Develop Presets each named for specific types of adjustment. The real grunt work in the process is to then move every Preset into the folder appropriate to its function. I try to break down the folder categories so that all the Presets within a folder can be viewed in Lightroom when every other folder has been collapsed. As a final step I've renamed as many of the Presets as necessary to achieve a consistent naming policy, again to help make selection easier.

While this kind of structure can be created from within Lightroom, the Develop Presets column is a pretty cramped workspace. I found it much easier to do the building work in the Finder (Explorer for Windows users), where you can work on the entire screen. From within Lightroom, Ctrl-click on one of the Presets you have created, then select "Show in Finder", this will reveal the location of the Develop Presets folder. Of course real men don't ask for directions, and will probably prefer to navigate themselves from their Home directory: Library/Application Support/Adobe/Lightroom/

Once there, it's simply a question of creating the desired number of folders and populating them with the lrtemplate files until they've all been relocated. I find it's easiest to do this filling the screen with two Finder windows and moving files from the one to the other. Once completed and Lightroom is reopened, the format created in the Finder will be almost exactly mirrored in Lightroom's Develop Presets column. (The Presets provided with Lightroom do not appear in the Finder).

The screenshot here shows where I am today, although of course it's always a work in progress, and we can hope that maybe a future version of Lightroom will incorporate a more sophisticated Preset management system.
Until that comes along, your reorganization work will gradually be lost unless you continue to apply the same principles when adding new Presets to your collection.